https://www.youngju.dev/blog 천천히 올바르게. AI Researcher & DevOps Engineer Youngju's tech blog. GPU/CUDA, LLM, MLOps, Kubernetes AI workloads, distributed training, and data engineering. ko fjvbn2003@gmail.com (Youngju Kim) fjvbn2003@gmail.com (Youngju Kim) Sat, 16 May 2026 00:00:00 GMT https://www.youngju.dev/blog/culture/2026-05-16-ai-biology-drug-discovery-2026-alphafold-3-rosettafold-esm-atlas-boltz-chai-rfdiffusion-isomorphic-recursion-deep-dive.en https://www.youngju.dev/blog/culture/2026-05-16-ai-biology-drug-discovery-2026-alphafold-3-rosettafold-esm-atlas-boltz-chai-rfdiffusion-isomorphic-recursion-deep-dive.en After the 2024 Nobel Prize in Chemistry went to protein design and AlphaFold, AI biology moved from academia to industry. From the technical differences between AlphaFold 3, RoseTTAFold All-Atom, ESM-3, Boltz-2, Chai-1, RFdiffusion, and ProteinMPNN, to the business models of Isomorphic Labs, Recursion, and Insilico Medicine, plus datasets like PDB, UniProt, ChEMBL and simulation infrastructure like GROMACS and DESMOND — and the AI bio ecosystems of Korea and Japan — this guide maps the hottest AI field of 2026 end to end. Sat, 16 May 2026 00:00:00 GMT fjvbn2003@gmail.com (Youngju Kim) ai-biologydrug-discoveryalphafoldrosettafoldesmboltzchairfdiffusionisomorphic-labsrecursioninsilico-medicineenglish https://www.youngju.dev/blog/culture/2026-05-16-ai-biology-drug-discovery-2026-alphafold-3-rosettafold-esm-atlas-boltz-chai-rfdiffusion-isomorphic-recursion-deep-dive.ja https://www.youngju.dev/blog/culture/2026-05-16-ai-biology-drug-discovery-2026-alphafold-3-rosettafold-esm-atlas-boltz-chai-rfdiffusion-isomorphic-recursion-deep-dive.ja 2024年のノーベル化学賞がタンパク質設計と AlphaFold に贈られて以降、AI 生物学は学術から産業へと移った。AlphaFold 3・RoseTTAFold All-Atom・ESM-3・Boltz-2・Chai-1・RFdiffusion・ProteinMPNN の技術的な違いから、Isomorphic Labs・Recursion・Insilico Medicine のビジネスモデル、PDB・UniProt・ChEMBL などのデータセットや GROMACS・DESMOND といったシミュレーション基盤、そして韓国・日本の AI バイオエコシステムまで — 2026 年現在もっとも熱い AI 分野を一気通貫で整理する。 Sat, 16 May 2026 00:00:00 GMT fjvbn2003@gmail.com (Youngju Kim) ai-biologydrug-discoveryalphafoldrosettafoldesmboltzchairfdiffusionisomorphic-labsrecursioninsilico-medicine日本語 https://www.youngju.dev/blog/culture/2026-05-16-ai-biology-drug-discovery-2026-alphafold-3-rosettafold-esm-atlas-boltz-chai-rfdiffusion-isomorphic-recursion-deep-dive https://www.youngju.dev/blog/culture/2026-05-16-ai-biology-drug-discovery-2026-alphafold-3-rosettafold-esm-atlas-boltz-chai-rfdiffusion-isomorphic-recursion-deep-dive 2024년 노벨 화학상이 단백질 설계와 AlphaFold에 돌아간 이후, AI 생물학은 학문에서 산업으로 이동했다. AlphaFold 3 · RoseTTAFold All-Atom · ESM-3 · Boltz-2 · Chai-1 · RFdiffusion · ProteinMPNN의 기술적 차이부터 Isomorphic Labs · Recursion · Insilico Medicine의 비즈니스 모델, PDB · UniProt · ChEMBL 같은 데이터셋과 GROMACS · DESMOND 같은 시뮬레이션 인프라, 그리고 한국·일본의 AI 바이오 생태계까지 — 2026년 현재 가장 뜨거운 AI 분야를 한 번에 정리한다. Sat, 16 May 2026 00:00:00 GMT fjvbn2003@gmail.com (Youngju Kim) ai-biologydrug-discoveryalphafoldrosettafoldesmboltzchairfdiffusionisomorphic-labsrecursioninsilico-medicine