https://www.youngju.dev/blog 천천히 올바르게. AI Researcher & DevOps Engineer Youngju's tech blog. GPU/CUDA, LLM, MLOps, Kubernetes AI workloads, distributed training, and data engineering. ko fjvbn2003@gmail.com (Youngju Kim) fjvbn2003@gmail.com (Youngju Kim) Sat, 16 May 2026 00:00:00 GMT https://www.youngju.dev/blog/culture/2026-05-16-ai-biology-drug-discovery-2026-alphafold-3-rosettafold-esm-atlas-boltz-chai-rfdiffusion-isomorphic-recursion-deep-dive.en https://www.youngju.dev/blog/culture/2026-05-16-ai-biology-drug-discovery-2026-alphafold-3-rosettafold-esm-atlas-boltz-chai-rfdiffusion-isomorphic-recursion-deep-dive.en After the 2024 Nobel Prize in Chemistry went to protein design and AlphaFold, AI biology moved from academia to industry. From the technical differences between AlphaFold 3, RoseTTAFold All-Atom, ESM-3, Boltz-2, Chai-1, RFdiffusion, and ProteinMPNN, to the business models of Isomorphic Labs, Recursion, and Insilico Medicine, plus datasets like PDB, UniProt, ChEMBL and simulation infrastructure like GROMACS and DESMOND — and the AI bio ecosystems of Korea and Japan — this guide maps the hottest AI field of 2026 end to end. Sat, 16 May 2026 00:00:00 GMT fjvbn2003@gmail.com (Youngju Kim) ai-biologydrug-discoveryalphafoldrosettafoldesmboltzchairfdiffusionisomorphic-labsrecursioninsilico-medicineenglish https://www.youngju.dev/blog/culture/2026-05-16-ai-biology-drug-discovery-2026-alphafold-3-rosettafold-esm-atlas-boltz-chai-rfdiffusion-isomorphic-recursion-deep-dive.ja https://www.youngju.dev/blog/culture/2026-05-16-ai-biology-drug-discovery-2026-alphafold-3-rosettafold-esm-atlas-boltz-chai-rfdiffusion-isomorphic-recursion-deep-dive.ja 2024年のノーベル化学賞がタンパク質設計と AlphaFold に贈られて以降、AI 生物学は学術から産業へと移った。AlphaFold 3・RoseTTAFold All-Atom・ESM-3・Boltz-2・Chai-1・RFdiffusion・ProteinMPNN の技術的な違いから、Isomorphic Labs・Recursion・Insilico Medicine のビジネスモデル、PDB・UniProt・ChEMBL などのデータセットや GROMACS・DESMOND といったシミュレーション基盤、そして韓国・日本の AI バイオエコシステムまで — 2026 年現在もっとも熱い AI 分野を一気通貫で整理する。 Sat, 16 May 2026 00:00:00 GMT fjvbn2003@gmail.com (Youngju Kim) ai-biologydrug-discoveryalphafoldrosettafoldesmboltzchairfdiffusionisomorphic-labsrecursioninsilico-medicine日本語 https://www.youngju.dev/blog/culture/2026-05-16-ai-biology-drug-discovery-2026-alphafold-3-rosettafold-esm-atlas-boltz-chai-rfdiffusion-isomorphic-recursion-deep-dive https://www.youngju.dev/blog/culture/2026-05-16-ai-biology-drug-discovery-2026-alphafold-3-rosettafold-esm-atlas-boltz-chai-rfdiffusion-isomorphic-recursion-deep-dive 2024년 노벨 화학상이 단백질 설계와 AlphaFold에 돌아간 이후, AI 생물학은 학문에서 산업으로 이동했다. AlphaFold 3 · RoseTTAFold All-Atom · ESM-3 · Boltz-2 · Chai-1 · RFdiffusion · ProteinMPNN의 기술적 차이부터 Isomorphic Labs · Recursion · Insilico Medicine의 비즈니스 모델, PDB · UniProt · ChEMBL 같은 데이터셋과 GROMACS · DESMOND 같은 시뮬레이션 인프라, 그리고 한국·일본의 AI 바이오 생태계까지 — 2026년 현재 가장 뜨거운 AI 분야를 한 번에 정리한다. Sat, 16 May 2026 00:00:00 GMT fjvbn2003@gmail.com (Youngju Kim) ai-biologydrug-discoveryalphafoldrosettafoldesmboltzchairfdiffusionisomorphic-labsrecursioninsilico-medicine https://www.youngju.dev/blog/culture/2026-05-16-ai-materials-science-chemistry-2026-deepmind-gnome-microsoft-mattergen-orbital-materials-citrine-informatics-schrodinger-rosettafold-all-atom-deep-dive.en https://www.youngju.dev/blog/culture/2026-05-16-ai-materials-science-chemistry-2026-deepmind-gnome-microsoft-mattergen-orbital-materials-citrine-informatics-schrodinger-rosettafold-all-atom-deep-dive.en Everything about AI for materials science and chemistry as of May 2026 in one read. DeepMind GNoMEs 2.2M stable crystals, Microsoft MatterGen and MatterSim, Orbital Materials Orb-v3, MACE, NequIP, Allegro and DeePMD-kit MLIPs, Materials Project, OQMD, AFLOW and JARVIS databases, Citrine and Schrödinger commercial platforms, RoseTTAFold All-Atom, Boltz-1 and Chai-1 drug design, IBM RXN and AiZynthFinder for synthesis planning, and Korean KIST, KIMS, POSTECH, Samsung, plus Japanese NIMS and PFN Matlantis are all covered. Sat, 16 May 2026 00:00:00 GMT fjvbn2003@gmail.com (Youngju Kim) ai-materialschemistry-aignome-deepmindmattergen-microsoftorbital-materialscitrine-informaticsschrodingerrosettafold-aaboltzmacenequipdpmdenglish https://www.youngju.dev/blog/culture/2026-05-16-ai-materials-science-chemistry-2026-deepmind-gnome-microsoft-mattergen-orbital-materials-citrine-informatics-schrodinger-rosettafold-all-atom-deep-dive.ja https://www.youngju.dev/blog/culture/2026-05-16-ai-materials-science-chemistry-2026-deepmind-gnome-microsoft-mattergen-orbital-materials-citrine-informatics-schrodinger-rosettafold-all-atom-deep-dive.ja 2026年5月時点の AI 材料科学・化学のすべてを 1 本で。DeepMind GNoME の 220 万安定結晶、Microsoft MatterGen と MatterSim、Orbital Materials Orb-v3、MACE・NequIP・Allegro・DeePMD-kit の MLIP、Materials Project・OQMD・AFLOW・JARVIS データベース、Citrine と Schrödinger の商用プラットフォーム、RoseTTAFold All-Atom・Boltz-1・Chai-1 の創薬、IBM RXN・AiZynthFinder の合成経路、さらに韓国 KIST・KIMS・POSTECH・サムスン、日本の NIMS・PFN Matlantis までを徹底整理する。 Sat, 16 May 2026 00:00:00 GMT fjvbn2003@gmail.com (Youngju Kim) ai-materialschemistry-aignome-deepmindmattergen-microsoftorbital-materialscitrine-informaticsschrodingerrosettafold-aaboltzmacenequipdpmd日本語 https://www.youngju.dev/blog/culture/2026-05-16-ai-materials-science-chemistry-2026-deepmind-gnome-microsoft-mattergen-orbital-materials-citrine-informatics-schrodinger-rosettafold-all-atom-deep-dive https://www.youngju.dev/blog/culture/2026-05-16-ai-materials-science-chemistry-2026-deepmind-gnome-microsoft-mattergen-orbital-materials-citrine-informatics-schrodinger-rosettafold-all-atom-deep-dive 2026년 5월 기준 AI 재료과학·화학의 모든 것을 한 글에서 본다. DeepMind GNoME가 발견한 2.2M개 안정 결정, Microsoft MatterGen·MatterSim, Orbital Materials Orb-v3, MACE·NequIP·Allegro·DeePMD-kit MLIP, Materials Project·OQMD·AFLOW·JARVIS 데이터베이스, Citrine·Schrödinger 상용 플랫폼, RoseTTAFold All-Atom·Boltz-1·Chai-1 약물 설계, IBM RXN·AiZynthFinder 합성 경로, 그리고 한국 KIST·KIMS·POSTECH·삼성, 일본 NIMS·PFN Matlantis까지 완전히 정리한다. Sat, 16 May 2026 00:00:00 GMT fjvbn2003@gmail.com (Youngju Kim) ai-materialschemistry-aignome-deepmindmattergen-microsoftorbital-materialscitrine-informaticsschrodingerrosettafold-aaboltzmacenequipdpmd